IN THE SPOTLIGHT Cancer Metastasis: Perivascular Macrophages Under Watch
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چکیده
906 | CANCER DISCOVERY SEPTEMBER 2015 www.aacrjournals.org Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. Corresponding Author: Michele De Palma, École Polytechnique Fédérale de Lausanne (EPFL), Station 19, CH-1015, Lausanne, Switzerland. Phone: 41-21-69-37271; Fax: 41-21-69-37271; E-mail: michele.depalma@epfl .ch doi: 10.1158/2159-8290.CD-15-0819 ©2015 American Association for Cancer Research. IN THE SPOTLIGHT Cancer Metastasis: Perivascular Macrophages Under Watch Ece Kadioglu and Michele De Palma Summary: TIE2-expressing macrophages cluster around blood vessels and sustain tumor angiogenesis. Harney and colleagues now use live imaging of mouse mammary tumors to show that these perivascular macrophages also promote the transient opening of tumor blood vessels to facilitate hematogenous cancer cell dissemination and metastasis. Cancer Discov; 5(9); 906–8. ©2015 AACR.
منابع مشابه
Cancer Metastasis: Perivascular Macrophages Under Watch.
TIE2-expressing macrophages cluster around blood vessels and sustain tumor angiogenesis. Harney and colleagues now use live imaging of mouse mammary tumors to show that these perivascular macrophages also promote the transient opening of tumor blood vessels to facilitate hematogenous cancer cell dissemination and metastasis.
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تاریخ انتشار 2015